• About FLEXYTE® Assays
• Epigenetics
  • HMTs
  • Deiminases
  • Demethylases
  • Epireader Histone Interactions
• Kinases
  • Ser/thr kinases
  • Tyrosine kinases
• Proteases
• Phosphatases
• Protein-Ligand Interactions
• Compound Interference
• Custom Assay Development
• Bulk Substrate Provision
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FLEXYTE® Ser/Thr Phosphatase Assay Platform

• Generic approach to assaying Ser/Thr phosphatases.
• Tailored substrates developed to meet the requirements of Ser/Thr phosphatases
• Phosphatase dephosphorylates peptide substrate and addition of SMC reduces the fluorescence lifetime of phosphorylated substrate only.  Hence, reaction is monitored by an increase in fluorescence lifetime of the dephosphorylated product